Extend Your Research Nationally With Us

Founded by Yale Research Investigators, Trusted Medical Research Institute (TMRI) conducts evidence-based healthcare research nationally leveraging physical Regional Extension Centers in 24 states.

What is the

Trusted Medical Research Institute?

TMRI is the 4th largest independent clinical research network in the country. The Institute functions as a resource to extend the research capabilities of academic medical centers and outside organizations, and allows for direct collaboration with Yale researchers, one of our main partners.

We manage physical Research Extension Centers™ in 24 states across the United States, giving researchers access to a nationwide network of direct-care clinics, merging key aspects of successful clinical trials from rapid, diverse participant recruitment, trial execution, and consumer market engagement. Along with our partners, we can scale subject matter expertise, virtual engagement, and onsite subject engagement at an unprecedented scale.

Security Built for

Government Standards

TMRI is the only research center fully built on a government-approved cloud infrastructure, delivering the highest level of data security, compliance, and trust for clinical research studies.

Academic Roots

Enabling Research Rigor

Founded by Yale Research Investigators, TMRI applies proven academic methodologies to build a robust, evidence-driven research program grounded in scientific integrity and real-world impact.

Nationwide

Research Reach

Leveraging our growing network of clinics in 24 states and licensed medical professionals in all 50 states, TMRI empowers clinical research to scale nationwide, bringing studies closer to diverse communities and participants.

Renowned Academic & Scientific Credibility

Unmatched Science

We team with the nation’s leading academic outcomes research organization, with experience spanning NIH, FDA, HHS, CMS, large payers, and pharmaceutical companies.

Empowered Participants

With a 98% patient satisfaction rating, provide white glove service to humans participating in research and empower at every step in the process

Unblocked Barriers

We combine our physical Reseach Extension Centers™ in 24 states and virtual engagement break down the geographic barriers that slow down access to diverse populations required to fuel discovery.

Research

Spotlight

TMRI is rooted in evidence-based research. We believe that research should infuse all levels of care and patient experiences to truly improve patient outcomes and are dedicated to moving potential improvements in medicine forward by participating in research projects that educate health care providers and potentially benefit patients.

Health & Weight Registry

The Ella Health & Weight Registry is our newest research initiative at TMRI. The registry provides a pool of consented volunteers that provides longitudinal health information based on periodic surveys of self-reported data. The Health & Weight Registry documents the experiences of people 18 and older with a BMI of 27 or higher. Participants who sign up for the registry may be connected to future clinical research studies related to weight management and obesity.

A Registry-enabled Accelerator for Trials

This initiative is designed to accelerate the path from bench to bedside for individuals affected by obesity. To do this, the Yale Researchers and Trusted Medical have created a participant-centered registry and research community. The registry potentially serves to: